I suggest you start by looking at the MoM website ( mom.gov.sg ), and informing yourself about the work visa possibilities. Maybe also on the ICA website (for non-working visas). Then, if you still have questions, come back here to the forum with some more details about your salary level, industry, years of experience, education level etc.
Note that your wife, if she wants to work, will have to get a work visa on her own merits. (With the exception of LOC - read about it on the MoM website.)