I've posted this on a female forum with my observation and research on the pill and how people react with the drug reductile -
I'm not particularly a fan of these kind of drugs but that's my judgment on myself but if you have to use it(lack of willpower - can't control your hunger, etc), proceed with caution.
You have to be careful, the appetite depressant cuts your caloric intake drastically.
If you cut your caloric intake by too much and stay on it - you're body will get metabolic damage.
Usually you'll have a ravenous appetite if you do that as a natural response to your starvation.
So when you get off the pills after an extend period of time without strategic damage control and eat normally again, even the same portion will cause you to gain fat(even if its little) and balloon up again. By then you'll try to starve yourself even more and form an addiction towards this method(using the pill to curb hunger) because you lose weight so slowly and gain it back so fast that you're eating like a bird; further more its not cheap - 110 per month's supply.
When you're eating too little, your body will shut down all your major systems/organs - immune/reproduction etc just to conserve energy. You'll waste your muscles just to make food for the brain and that kills your metabolism almost immediately.
This is not forgetting getting gastric problems that will plague you for LIFE!
If you have to use it, count your calories and make sure you meet your caloric requirement and no lesser, cycle it every 8 weeks and get off it and consume maintainence level to return the metabolism back to optimal levels.
How to calculate your caloric requirement - BW(lbs) x 15 is your maintenance (adjust accordingly - getting fatter means too much, losing weight means too little)/ - 20% is a good gauge for lose weight (adjust to real world results but don't be greedy, keep it constant unless you have no choice to cut more calories).
Have about 0.9 grams of protein to prevent muscle wasting and do a mix of cardio and resistance exercise.
Cardio helps to expand calories while resistance exercises help to maintain muscles - your body will find ways to get rid of muscles as its expensive to maintain. It is a passive fat/weight loss tool and together with cardio - active, it'll be the fastest way to get to your desired weight/dress size/waist line.
REMEMBER CYCLE! 8 weeks 1-2 weeks off 8 weeks again.
This will save you the problem of the metabolic damage.
Don't be lazy and dependant on the drug; sure it'll work, but you're harming yourself in the long run and when that happens, paying the cost of it in health care(if your body don't kill you, the unending turmoil of finding money to fix your health will) -
http://www.figureathlete.com/free_on..._damage_part_i
Hope you people take this warning seriously and know how to use it responsibly rather than non-chalantly without regards to the potential dangers for your body when you indulge in a drug like this.