Having read a number of posts on this forum about this very topic, I found some responses very helpful, informative and deep. I seek your wise counsel on my own case:
Indian male (31) with 10 years in Singapore. Currently on EP.
Working in retail banking and client service with a global heavyweight bank
Earning annually about $62k basic + $15k annual bonus
Undergrad: engineering from NIT Trichy, India
Postgrad: engineering from NUS, SG (2012 master's degree, no tuition grant availed as I fully self funded)
Last year gained a certificate off being a blockchain expert (FinTech stuff) to align myself with Singapore's future growth (digital innovation and service hub) but yet to gain any hands on experience or project work in this field despite my efforts to penetrate.
Tax payer for 9 years
Been winning customer service recognition awards (EXSA) for past 4-5 years now for championing the customer service spirit at work.
Also minor involvement in Singapore cultural scene (supporting artist in music performances in Hindu temples and student/participant in Indian classical music houses). Not much for charitable donations apart from a couple hundred each year

Spouse: Indian female (31), currently on dependent pass, joined me in 2020 Jan.
Undergrad and postgrad#1 in art history, Indian College. Now doing postgrad#2 in NTU, self funding, no MOE subsidy/scholarship etc. Studying in her dependents pass basically. Her work experience is varied, from teaching to corporate communications.
We don't have any children yet but likely in a couple of years.
Apart from my ethnicity and passport putting me at a disadvantage, anything else to tailor about my story and other suggestions from you will be gratefully considered.
Plus specifically: how to put this qualitative info about myself into my PR application (form seems fairly straightforward and requested info very specific)
Also, will my wife having lived in Singapore for less than 2 years make her ineligible for PR even though I'm including her in my PTS scheme application?
Many thanks!